STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysESerine O-acetyltransferase; Catalyses the first step of the synthesis of L-cysteine from L-serine. (194 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase; Responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.998
AARI_17900
Identified by match to PF00291: pyridoxal-phosphate dependent enzyme.
  
 0.967
AARI_24020
Catalyses the synthesis of L-cystathionine from L-serine and L-homocysteine.
 
 0.959
sdaA
Catalyzes the dehydratation of L-serine into ammonia and pyruvate; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.927
cysS
cysteine--tRNA ligase; Activates cysteine and transfers it to tRNA(Cys) as the first step in protein biosynthesis; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.904
cysS-2
cysteine--tRNA ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
  
 0.865
ilvA
Catalyzes the conversion of threonine into 2-oxobutanoate. Involved in isoleucine biosynthesis. The enzyme from a number of sources also acts on L-serine.
    
 0.852
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.825
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.825
metB
Cystathionine gamma-synthase; Catalyzes the conversion of cysteine and succinyl-homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms.
  
  
 0.824
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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