node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARI_15650 | msrA | AARI_15650 | AARI_15640 | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.615 |
AARI_17740 | AARI_24650 | AARI_17740 | AARI_24650 | Identified by match to protein family PF00462. | Putative glutaredoxin; Identified by match to PF05768: glutaredoxin-like domain (DUF836). This family contains several viral glutaredoxins, and many related bacterial and eukaryotic proteins of unknown function. Glutaredoxins are small proteins of approximately one hundred amino-acid residues which utilise glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. | 0.448 |
AARI_17740 | msrA | AARI_17740 | AARI_15640 | Identified by match to protein family PF00462. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.834 |
AARI_24610 | msrA | AARI_24610 | AARI_15640 | Redoxin domain-containing protein; Identified by match to protein family PF08534. This family of redoxins includes peroxiredoxin, thioredoxin and glutaredoxin proteins. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.869 |
AARI_24610 | msrB | AARI_24610 | AARI_19790 | Redoxin domain-containing protein; Identified by match to protein family PF08534. This family of redoxins includes peroxiredoxin, thioredoxin and glutaredoxin proteins. | Peptide-methionine (R)-S-oxide reductase; Plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged. | 0.625 |
AARI_24650 | AARI_17740 | AARI_24650 | AARI_17740 | Putative glutaredoxin; Identified by match to PF05768: glutaredoxin-like domain (DUF836). This family contains several viral glutaredoxins, and many related bacterial and eukaryotic proteins of unknown function. Glutaredoxins are small proteins of approximately one hundred amino-acid residues which utilise glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. | Identified by match to protein family PF00462. | 0.448 |
AARI_24650 | msrA | AARI_24650 | AARI_15640 | Putative glutaredoxin; Identified by match to PF05768: glutaredoxin-like domain (DUF836). This family contains several viral glutaredoxins, and many related bacterial and eukaryotic proteins of unknown function. Glutaredoxins are small proteins of approximately one hundred amino-acid residues which utilise glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.653 |
AARI_25690 | msrA | AARI_25690 | AARI_15640 | NHL repeat-containing protein; Match to PF01436: NHL repeat. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.869 |
AARI_25690 | msrB | AARI_25690 | AARI_19790 | NHL repeat-containing protein; Match to PF01436: NHL repeat. | Peptide-methionine (R)-S-oxide reductase; Plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged. | 0.625 |
AARI_26400 | msrA | AARI_26400 | AARI_15640 | 6 Protein of unknown function, without similarity to other proteins. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.869 |
AARI_26400 | msrB | AARI_26400 | AARI_19790 | 6 Protein of unknown function, without similarity to other proteins. | Peptide-methionine (R)-S-oxide reductase; Plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged. | 0.625 |
msrA | AARI_15650 | AARI_15640 | AARI_15650 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. | 0.615 |
msrA | AARI_17740 | AARI_15640 | AARI_17740 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Identified by match to protein family PF00462. | 0.834 |
msrA | AARI_24610 | AARI_15640 | AARI_24610 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Redoxin domain-containing protein; Identified by match to protein family PF08534. This family of redoxins includes peroxiredoxin, thioredoxin and glutaredoxin proteins. | 0.869 |
msrA | AARI_24650 | AARI_15640 | AARI_24650 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Putative glutaredoxin; Identified by match to PF05768: glutaredoxin-like domain (DUF836). This family contains several viral glutaredoxins, and many related bacterial and eukaryotic proteins of unknown function. Glutaredoxins are small proteins of approximately one hundred amino-acid residues which utilise glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. | 0.653 |
msrA | AARI_25690 | AARI_15640 | AARI_25690 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | NHL repeat-containing protein; Match to PF01436: NHL repeat. | 0.869 |
msrA | AARI_26400 | AARI_15640 | AARI_26400 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 6 Protein of unknown function, without similarity to other proteins. | 0.869 |
msrA | msrB | AARI_15640 | AARI_19790 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Peptide-methionine (R)-S-oxide reductase; Plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged. | 0.996 |
msrA | nrdH | AARI_15640 | AARI_17850 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Glutaredoxin electron transport component NrdH; Electron transport system for the ribonucleotide reductase system nrdEF. | 0.672 |
msrA | nrdH-2 | AARI_15640 | AARI_30340 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Glutaredoxin electron transport component NrdH; Electron transport system for the ribonucleotide reductase system nrdEF. | 0.672 |