STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AARI_16970Putative DNA uptake protein; Helix-hairpin-helix DNA-binding domain. The HhH motif is an around 20 amino acids domain present in prokaryotic and eukaryotic non-sequence-specific DNA binding proteins. (215 aa)    
Predicted Functional Partners:
Putative competence protein; Identified by match to protein family PF03772, some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. 10 transmembrane helices predicted by TMHMM2.0.
Identified by match to protein family PF02645: uncharacterised protein, DegV family COG1307. The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular function of fatty-acid binding and may play a role in the cellular functions of fatty acid transport or metabolism.
leucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
Putative cell envelope-related transcriptional attenuator.
Putative cell envelope-related transcriptional attenuator.
Match to PF01478: Type IV leader peptidase family. This group of aspartic endopeptidases belong to MEROPS peptidase family A24 (type IV prepilin peptidase family, clan AD), subfamily A24A. Possibly involved in protein secretion.
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
Cell division protein FtsW; Plays a role in the stabilization of the FtsZ ring during cell division; Belongs to the SEDS family.
Putative serine/threonine protein kinase; Identified by match to protein domain PD000001. Match to PS00108 pattern. Protein kinases are a group of enzymes that possess a catalytic subunit which transfers the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. They play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation.
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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