STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
 0.999
aroE
Fourth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p-aminobenzoic acid, folate and ubiquinone.
  
 0.997
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 0.996
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 0.994
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.991
aroG
3-deoxy-7-phosphoheptulonate synthase; Involved in phenylalanine, tyrosine and tryptophan biosynthesis; Belongs to the class-II DAHP synthase family.
 
  
 0.975
AARI_26000
Shikimate dehydrogenase-like protein; Shikimate dehydrogenase is the fourth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p- aminobenzoic acid, folate and ubiquinone.
  
 0.971
AARI_07420
Identified by match to protein family PF02541. Similar to exopolyphosphatase (Ppx, EC 3.6.1.11) and guanosine pentaphosphate phospho-hydrolase (GppA, EC 3.6.1. 40) proteins.
 
 
    0.905
tyrA
Catalyses the following reaction: prephenate + NAD(+) <=> 4-hydroxyphenylpyruvate + CO(2) + NADH. Involved in tyrosine biosynthesis.
 
  
 0.887
AARI_17230
5.2 Protein of unknown function similar to proteins from other organisms.
       0.796
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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