node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARI_03550 | pdxS | AARI_03550 | AARI_17600 | Putative phosphomethylpyrimidine kinase; EC 2.7.4.7 is involved in thiamin biosynthesis. It catalyzes the phosphorylation of HMP-P to HMP-PP. | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.913 |
AARI_03550 | pdxT | AARI_03550 | AARI_17500 | Putative phosphomethylpyrimidine kinase; EC 2.7.4.7 is involved in thiamin biosynthesis. It catalyzes the phosphorylation of HMP-P to HMP-PP. | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.913 |
AARI_31590 | AARI_31600 | AARI_31590 | AARI_31600 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | 0.999 |
AARI_31590 | pdxS | AARI_31590 | AARI_17600 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.809 |
AARI_31590 | pdxT | AARI_31590 | AARI_17500 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
AARI_31590 | pgi | AARI_31590 | AARI_18890 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Glucose-6-phosphate isomerase; Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. Also catalyzes the anomerization of D-glucose-6-phosphate; Belongs to the GPI family. | 0.915 |
AARI_31590 | prs | AARI_31590 | AARI_07970 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.907 |
AARI_31590 | rbsK | AARI_31590 | AARI_27570 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.907 |
AARI_31590 | rpi | AARI_31590 | AARI_18550 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Ribose-5-phosphate isomerase; Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate. Involved in the pentose phosphate pathway. | 0.939 |
AARI_31590 | tal | AARI_31590 | AARI_18880 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.982 |
AARI_31590 | tkt | AARI_31590 | AARI_18870 | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | Transketolase; Catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to ribose 5-phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. The second reaction catalyzed by transketolase involves the transfer of a 2-carbon fragment from D-xylulose 5-phosphate to the aldose D-erythrose-4-phosphate, affording fructose-6-phosphate and glyceraldehyde 3-phosphate. | 0.921 |
AARI_31600 | AARI_31590 | AARI_31600 | AARI_31590 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Identified by match to PF00456: transketolase, thiamine diphosphate binding domain. | 0.999 |
AARI_31600 | pdxS | AARI_31600 | AARI_17600 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.808 |
AARI_31600 | pdxT | AARI_31600 | AARI_17500 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
AARI_31600 | pgi | AARI_31600 | AARI_18890 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Glucose-6-phosphate isomerase; Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. Also catalyzes the anomerization of D-glucose-6-phosphate; Belongs to the GPI family. | 0.907 |
AARI_31600 | prs | AARI_31600 | AARI_07970 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.908 |
AARI_31600 | rbsK | AARI_31600 | AARI_27570 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.904 |
AARI_31600 | rpi | AARI_31600 | AARI_18550 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Ribose-5-phosphate isomerase; Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate. Involved in the pentose phosphate pathway. | 0.934 |
AARI_31600 | tal | AARI_31600 | AARI_18880 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.987 |
AARI_31600 | tkt | AARI_31600 | AARI_18870 | Identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C-terminal domain). | Transketolase; Catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to ribose 5-phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. The second reaction catalyzed by transketolase involves the transfer of a 2-carbon fragment from D-xylulose 5-phosphate to the aldose D-erythrose-4-phosphate, affording fructose-6-phosphate and glyceraldehyde 3-phosphate. | 0.929 |