STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ssbSingle-stranded DNA-binding protein; This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair. (149 aa)    
Predicted Functional Partners:
ssb-2
Single-stranded DNA-binding protein; This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair.
  
  
 
0.906
AARI_03700
Single-stranded DNA-binding protein; Identified by match to PF00436. The Escherichia coli single-strand binding protein binds tightly to single-stranded DNA (ss-DNA) and plays an important role in DNA replication, recombination and repair. Closely related variants of SSB are encoded in the genome of a variety of large self-transmissible plasmids.
     
  0.900
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
  
 0.775
priA
Putative primosomal protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
   
 
 0.700
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
   
 
 0.684
dnaE
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; Belongs to the DNA polymerase type-C family. DnaE2 su [...]
   
 
 0.680
dnaE-2
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
   
 
 0.680
AARI_05190
Putative DNA polymerase III subunit delta prime; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
   
 
 0.677
AARI_18640
TCDB: ATP-binding cassette (ABC) superfamily, (putative) drug resistance ATPase-2 (Drug RA2) family (TC 3.A.1.121.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family, ARE-subfamily (antibiotic resistance).
 
    0.650
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.625
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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