STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiOGlycine oxidase; Required for the biosynthesis of the thiazole moiety of thiamine diphosphate. (370 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.999
thiS
thiamineS; Sulfur carrier protein involved in thiamin biosynthesis : carries the sulfur needed for thiazole assembly on its carboxy terminus (ThiS-COSH).
  
  
 0.896
thiF
Adenylyltransferase ThiF; Catalyzes the adenylation by ATP of the carboxyl-terminal glycine of ThiS, as part of the biosynthesis pathway of thiamin pyrophosphate (vitamin B1).
 
  
 0.860
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.842
soxA
Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine and forms equimolar amounts of formaldehyde, glycine and hydrogen peroxide.
  
 
 0.736
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
      
 0.716
AARI_21830
Putative GNAT-family acetyltransferase; Identified by match to PF00583: acetyltransferase (GNAT) family.
       0.675
AARI_27900
Putative 3-phenylpropionate dioxygenase ferredoxin reductase subunit; 3-phenylpropionate dioxygenase converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol). Involved in the catabolism of 3-phenylpropionic acid.
  
 
 0.593
thiD
Phosphomethylpyrimidine kinase; Involved in thiamin biosynthesis. Catalyzes the phosphorylation of HMP-P to HMP-PP.
 
  
 0.561
AARI_03550
Putative phosphomethylpyrimidine kinase; EC 2.7.4.7 is involved in thiamin biosynthesis. It catalyzes the phosphorylation of HMP-P to HMP-PP.
 
  
 0.521
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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