STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AARI_24020Catalyses the synthesis of L-cystathionine from L-serine and L-homocysteine. (454 aa)    
Predicted Functional Partners:
metB-3
Cystathionine gamma-synthase; Catalyzes the conversion of cysteine and succinyl-homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms.
 0.993
metB-2
Cystathionine gamma-synthase; Catalyzes the conversion of cysteine and succinyl-homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms.
 0.978
metB
Cystathionine gamma-synthase; Catalyzes the conversion of cysteine and succinyl-homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms.
 0.972
cysE
Serine O-acetyltransferase; Catalyses the first step of the synthesis of L-cysteine from L-serine.
 
 0.959
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.929
ilvA
Catalyzes the conversion of threonine into 2-oxobutanoate. Involved in isoleucine biosynthesis. The enzyme from a number of sources also acts on L-serine.
 
 
 0.928
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.927
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.927
AARI_02460
O-acetylhomoserine aminocarboxypropyltransferase; Catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol.
 
 
 0.912
AARI_07000
O-acetylhomoserine aminocarboxypropyltransferase; Catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol.
 
 
 0.912
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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