STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AARI_25070Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (51 aa)    
Predicted Functional Partners:
AARI_21660
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
  
     0.773
AARI_25060
Putative endoribonuclease; Identified by match to protein domain PF01042: endoribonuclease L-PSP; endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis.
  
    0.761
AARI_25080
Penicillin-binding protein; Match to PF00912 and PF00905. Transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan chains. Possibly involved in peptidoglycan biosynthesis.
       0.673
AARI_25050
NUDIX hydrolase; Identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain ce [...]
       0.641
AARI_25090
Match to protein domain PF00149. The metallophosphoesterase motif is found in a large number of proteins invoved in phosphoryation. These include serine/threonine phosphatases, DNA polymerase, exonucleases, and other phosphatases.
 
     0.638
mtrB
Sensor histidine kinase MtrB; Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates MtrA in response to environmental signals.
  
     0.405
AARI_00040
Conserved hypothetical protein; Match to protein family PF05258. This family contains several actinomycete proteins of unknown function.
  
     0.403
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.