STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AARI_28030Cysteine-rich domain-containing protein; Identified by match to PF02754. This domain is usually found in two copies per protein. It contains up to four conserved cysteines. The group includes proteins characterised as: heterodisulphide reductase, subunit B (HrdB); succinate dehydrogenase, subunit C (SdhC); Fe-S oxidoreductase; glycerol-3-phosphate dehydrogenase subunit C (Anaerobic GlpC, ); and glycolate oxidase iron-sulfur subunit (GlcF). (254 aa)    
Predicted Functional Partners:
AARI_28040
Iron-sulfur cluster binding protein; Identified by match to protein family TIGR00273.
 
 0.998
AARI_28050
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
 
 0.984
AARI_28020
Putative lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.788
sdhB
The succinate dehydrogenase complex catalyses the interconversion of fumarate and succinate. It contains several subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and membrane anchor proteins (SdhC and SdhD). Involved in the TCA cycle.
 
 
 
 0.755
AARI_28010
GntR-family transcriptional regulator; Identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships.
 
   
 0.583
AARI_27940
Putative lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.491
AARI_28060
MFS superfamily transporter; Major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily).
       0.419
glpD
Catalyzes the following reaction: sn-glycerol-3-phosphate + acceptor = glycerone phosphate + reduced acceptor. In bacteria, it is associated with the utilization of glycerol coupled to respiration.
  
  
 0.418
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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