STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
allBAllantoinase; Hydrolyzes allantoin into allantoate. Involved in purine degradation. (460 aa)    
Predicted Functional Partners:
pyrB
Catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoylaspartate, the second step in the de novo biosynthesis of pyrimidine; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.993
AARI_33730
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms.
 
  
 0.980
hyuE
Putative hydantoin racemase; Identified by similarity to protein SP:Q00924 (Pseudomonas sp. strain NS671). Match to protein family PF01177: Asp/Glu/Hydantoin racemase. Hydantoin racemase is responsible for racemization of the D-5-substituted hydantoins to their corresponding L-amino acids.
  
 0.978
carA
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit; Carbamoyl-phosphate synthase is involved in both arginine and pyrimidine biosynthesis and catalyzes the ATP-dependent formation of carbamoyl-phosphate from glutamine and carbon dioxide. In bacteria it is composed of two subunits: a large chain (gene carB) and a small chain (gene carA); Belongs to the CarA family.
 
  
 0.964
carB
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit; Carbamoyl-phosphate synthase is involved in both arginine and pyrimidine biosynthesis and catalyzes the ATP-dependent formation of carbamoyl-phosphate from glutamine and carbon dioxide. In bacteria it is composed of two subunits: a large chain (gene carB) and a small chain (gene carA); Belongs to the CarB family.
 
 0.962
AARI_31520
Allantoate deiminase catalyses the conversion of allantoate in ammonia, carbon dioxide andureidoglycolate. Involved in purine degradation.
 
 
 0.945
glxK
Glycerate kinase; Catalyses the following reaction: ATP + (R)-glycerate <=> ADP + 3-phospho-(R)-glycerate; Belongs to the glycerate kinase type-1 family.
 
    0.914
AARI_33710
Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
  
 0.838
AARI_33720
Putative hydroxyisourate hydrolase; Identified by match to PF00576: HIUase/Transthyretin family. This family includes transthyretin that is a thyroid hormone-binding protein that transports thyroxine from the bloodstream to the brain. However, most of the sequences listed in this family do not bind thyroid hormones. They are actually enzymes of the purine catabolism that catalyse the conversion of 5-hydroxyisourate (HIU) to 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5- carboxylate (OHCU). HIU hydrolysis is the original function of the family and is conserved from bacteria to mam [...]
 
   
 0.808
AARI_33420
Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the HpcH/HpaI aldolase family.
 
    0.794
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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