STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
catRTranscriptional regulator CatR; Possibly involved in the regulation of the catechol catabolism.Match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. (308 aa)    
Predicted Functional Partners:
catB
Muconate cycloisomerase; Identified by similarity to protein SP:Q76CC6 (Arthrobacter sp.). Involved in the degradation of aromatic compounds by converting cis,cis-muconate, the product of catechol ring cleavage to (4S)-muconolactone; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
     0.859
catC
Muconolactone Delta-isomerase; Catalyses the third step in the catabolism of catechol to succinyl-CoA and acetyl-CoA in the beta-ketoadipate pathway; Belongs to the muconolactone Delta-isomerase family.
 
   
 0.827
AARI_28250
LysR-family transcriptional regulator; Identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority [...]
  
     0.690
catA
Catechol 1,2-dioxygenase; Catalyses the third step in the catabolism of catechol to succinyl-CoA and acetyl-CoA in the beta-ketoadipate pathway: the intradiol cleavage reaction of catechol to form cis,cis-muconate.
 
   
 0.639
AARI_09020
LysR-family transcriptional regulator; Identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority [...]
  
     0.509
gltB
Glutamate synthase (NADPH) subunit alpha; Glutamate synthase participates in the ammonia assimilation process by catalyzing the formation of glutamate from glutamine and 2-oxoglutarate.
  
  
 0.403
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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