STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galKGalactokinase; Catalyzes the conversion of galactose to galactose 1-phosphate, first step of the Leloir pathway; Belongs to the GHMP kinase family. GalK subfamily. (398 aa)    
Predicted Functional Partners:
galT
UDP-glucose--hexose-1-phosphate uridylyltransferase; Involved in conversion of galactose into alpha-D-glucose 1-phosphate, second step of the Leloir pathway.
 0.999
AARI_33620
Putative aldose 1-epimerase; Identified by match to protein family PF1263. Aldose 1-epimerase (mutarotase) is the enzyme responsible for the anomeric interconversion of D-glucose and other aldoses (L-arabinose, D-xylose, D-galactose, maltose and lactose) between their alpha- and beta-forms.
  
 0.977
galE-2
Catalyses the formation of UDP-glucose from UDP-galactose. Involved in the catabolism of galactose.
 
 
 0.971
galE
Catalyses the formation of UDP-glucose from UDP-galactose. Involved in the catabolism of galactose; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
 0.880
AARI_33560
DeoR-family transcriptional regulator; DeoR-like transcription repressors occur in diverse bacteria as regulators of sugar and nucleoside metabolic systems. The effector molecules for deoR-like regulators are generally phosphorylated intermediates of the relevant metabolic pathway.
     
 0.842
lacZ
Beta-galactosidase; Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. Some enzymes in this group hydrolyze alpha-L-arabinosides.
 
  
 0.815
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.727
galU
UTP--glucose-1-phosphate uridylyltransferase; Catalyses the formation of UDP-glucose from glucose-1-phosphate.
     
 0.718
AARI_27410
Oxidoreductase domain-containing protein; Identified by match to PF01408 (oxidoreductase family, NAD-binding Rossmann fold) and PF02894 (oxidoreductase family, C-terminal alpha/beta domain).
 
 
 0.717
AARI_33520
Oxidoreductase domain-containing protein; Identified by match to PF01408 (oxidoreductase family, NAD-binding Rossmann fold).
 
 
 0.716
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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