STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.984
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
 
 0.972
EHM42209.1
Hypothetical protein; Belongs to the RemA family.
  
    0.961
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.941
EHM42208.1
TIGR00255-like family protein; Psort location: Cytoplasmic, score: 9.97.
 
    0.930
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.903
EHM40683.1
KEGG: vpr:Vpar_1386 6.0e-154 ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97.
 
  
   0.895
EHM41330.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
    
 0.887
EHM43392.1
KEGG: afn:Acfer_1856 5.3e-59 phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.878
EHM39373.1
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.846
Your Current Organism:
Anaeroglobus geminatus
NCBI taxonomy Id: 861450
Other names: A. geminatus F0357, Anaeroglobus geminatus F0357, Anaeroglobus geminatus str. F0357, Anaeroglobus geminatus strain F0357
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