| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHM41035.1 | EHM41160.1 | HMPREF0080_01055 | HMPREF0080_01032 | Queuosine biosynthesis protein QueD; KEGG: eel:EUBELI_20139 3.0e-42 6-pyruvoyl tetrahydrobiopterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.727 |
| EHM41035.1 | EHM41161.1 | HMPREF0080_01055 | HMPREF0080_01033 | Queuosine biosynthesis protein QueD; KEGG: eel:EUBELI_20139 3.0e-42 6-pyruvoyl tetrahydrobiopterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.493 |
| EHM41035.1 | EHM41162.1 | HMPREF0080_01055 | HMPREF0080_01034 | Queuosine biosynthesis protein QueD; KEGG: eel:EUBELI_20139 3.0e-42 6-pyruvoyl tetrahydrobiopterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | KEGG: vpr:Vpar_0493 1.4e-37 GTP cyclohydrolase I; K01495 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 9.97. | 0.957 |
| EHM41158.1 | EHM41159.1 | HMPREF0080_01030 | HMPREF0080_01031 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | 0.989 |
| EHM41158.1 | EHM41160.1 | HMPREF0080_01030 | HMPREF0080_01032 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.773 |
| EHM41158.1 | EHM41161.1 | HMPREF0080_01030 | HMPREF0080_01033 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.771 |
| EHM41158.1 | EHM41162.1 | HMPREF0080_01030 | HMPREF0080_01034 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | KEGG: vpr:Vpar_0493 1.4e-37 GTP cyclohydrolase I; K01495 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 9.97. | 0.852 |
| EHM41158.1 | EHM41664.1 | HMPREF0080_01030 | HMPREF0080_00886 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | Putative GTP cyclohydrolase II; KEGG: cpb:Cphamn1_0629 3.3e-43 3,4-dihydroxy-2-butanone 4-phosphate synthase; K01497 GTP cyclohydrolase II K02858; Psort location: Cytoplasmic, score: 9.97. | 0.790 |
| EHM41158.1 | ribB | HMPREF0080_01030 | HMPREF0080_00885 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.790 |
| EHM41159.1 | EHM41158.1 | HMPREF0080_01031 | HMPREF0080_01030 | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | 0.989 |
| EHM41159.1 | EHM41160.1 | HMPREF0080_01031 | HMPREF0080_01032 | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.842 |
| EHM41159.1 | EHM41161.1 | HMPREF0080_01031 | HMPREF0080_01033 | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.740 |
| EHM41159.1 | EHM41162.1 | HMPREF0080_01031 | HMPREF0080_01034 | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | KEGG: vpr:Vpar_0493 1.4e-37 GTP cyclohydrolase I; K01495 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 9.97. | 0.801 |
| EHM41159.1 | EHM41664.1 | HMPREF0080_01031 | HMPREF0080_00886 | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | Putative GTP cyclohydrolase II; KEGG: cpb:Cphamn1_0629 3.3e-43 3,4-dihydroxy-2-butanone 4-phosphate synthase; K01497 GTP cyclohydrolase II K02858; Psort location: Cytoplasmic, score: 9.97. | 0.726 |
| EHM41159.1 | ribB | HMPREF0080_01031 | HMPREF0080_00885 | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.726 |
| EHM41160.1 | EHM41035.1 | HMPREF0080_01032 | HMPREF0080_01055 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Queuosine biosynthesis protein QueD; KEGG: eel:EUBELI_20139 3.0e-42 6-pyruvoyl tetrahydrobiopterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | 0.727 |
| EHM41160.1 | EHM41158.1 | HMPREF0080_01032 | HMPREF0080_01030 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bbe:BBR47_52010 4.0e-51 two-component sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | 0.773 |
| EHM41160.1 | EHM41159.1 | HMPREF0080_01032 | HMPREF0080_01031 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: bde:BDP_0386 6.8e-43 vicR; response regulator protein VicR K07776; Psort location: Cytoplasmic, score: 9.97. | 0.842 |
| EHM41160.1 | EHM41161.1 | HMPREF0080_01032 | HMPREF0080_01033 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| EHM41160.1 | EHM41162.1 | HMPREF0080_01032 | HMPREF0080_01034 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: vpr:Vpar_0493 1.4e-37 GTP cyclohydrolase I; K01495 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 9.97. | 0.999 |