STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaAGMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. (511 aa)    
Predicted Functional Partners:
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
    0.999
argS
arginine--tRNA ligase; KEGG: vpr:Vpar_1585 1.6e-192 arginyl-tRNA synthetase; K01887 arginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.999
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 0.999
EHM39266.1
KEGG: vpr:Vpar_0361 1.4e-234 phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: Cytoplasmic, score: 9.26.
  
  
 0.994
EHM39267.1
Hypothetical protein; KEGG: vpr:Vpar_0361 1.1e-68 phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase.
  
  
 0.994
EHM39268.1
Hypothetical protein; KEGG: bde:BDP_0725 4.6e-12 purL; PurL phosphoribosylformylglycinamidine synthase K01952.
  
  
 0.994
EHM40823.1
CBS domain protein; KEGG: npu:Npun_R5794 1.2e-13 signal transduction protein; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.986
EHM42197.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
 0.982
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
 
 0.981
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.980
Your Current Organism:
Anaeroglobus geminatus
NCBI taxonomy Id: 861450
Other names: A. geminatus F0357, Anaeroglobus geminatus F0357, Anaeroglobus geminatus str. F0357, Anaeroglobus geminatus strain F0357
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