STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHM38774.1Haloacid dehalogenase-like hydrolase; KEGG: slg:SLGD_01206 1.4e-49 phosphoserine phosphatase, putative; Psort location: Cytoplasmic, score: 8.96. (374 aa)    
Predicted Functional Partners:
hisI
KEGG: bts:Btus_2167 1.4e-49 phosphoribosyl-ATP diphosphatase; K11755 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97; In the N-terminal section; belongs to the PRA-CH family.
  
    0.818
EHM42697.1
KEGG: bha:BH0844 1.5e-26 PTS system, glucose-specific enzyme II, A component; K02763 PTS system, D-glucosamine-specific IIA component; K02764 PTS system, D-glucosamine-specific IIB component K02765; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
  0.799
hisF
Imidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.785
hisA
KEGG: oih:OB0548 4.3e-57 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase K01814; Psort location: Cytoplasmic, score: 9.97.
  
    0.777
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.772
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-19 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family.
    
  0.752
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
   
 
  0.749
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.747
EHM43837.1
KEGG: afn:Acfer_1608 1.0e-64 prephenate dehydratase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97.
  
 
  0.660
EHM38768.1
KEGG: tpd:Teth39_0518 2.1e-39 hisB; imidazoleglycerol-phosphate dehydratase K01693; Psort location: Cytoplasmic, score: 9.97.
    
  0.620
Your Current Organism:
Anaeroglobus geminatus
NCBI taxonomy Id: 861450
Other names: A. geminatus F0357, Anaeroglobus geminatus F0357, Anaeroglobus geminatus str. F0357, Anaeroglobus geminatus strain F0357
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