STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (346 aa)    
Predicted Functional Partners:
EHM37813.1
Chorismate binding enzyme; KEGG: msi:Msm_1146 3.2e-155 anthranilate/para-aminobenzoate synthase component I, TrpE K01657; Psort location: Cytoplasmic, score: 9.97.
 0.999
EHM37815.1
KEGG: vpr:Vpar_0159 6.7e-36 glutamine amidotransferase of anthranilate synthase; K01658 anthranilate synthase component II; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
trpC
KEGG: rsd:TGRD_119 4.2e-66 indole-3-glycerol phosphate synthase; K01609 indole-3-glycerol phosphate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the TrpC family.
 
 0.999
trpF
KEGG: csh:Closa_3624 2.4e-40 phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.997
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.996
EHM37814.1
Hypothetical protein; KEGG: ere:EUBREC_2979 4.2e-11 anthranilate/para-aminobenzoate synthase component II, TrpG; K01658 anthranilate synthase component II; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.960
EHM43837.1
KEGG: afn:Acfer_1608 1.0e-64 prephenate dehydratase; K04093 chorismate mutase K04518; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.899
EHM43512.1
III protein, CoA-transferase family; KEGG: aco:Amico_1323 6.9e-114 formyl-CoA transferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the CoA-transferase III family.
 
      0.880
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.755
Your Current Organism:
Anaeroglobus geminatus
NCBI taxonomy Id: 861450
Other names: A. geminatus F0357, Anaeroglobus geminatus F0357, Anaeroglobus geminatus str. F0357, Anaeroglobus geminatus strain F0357
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