STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHI76311.1Sortase family protein. (246 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.856
EHI76310.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.566
EHI77168.1
single-stranded-DNA-specific exonuclease RecJ.
     
 0.550
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
    0.542
EHI77855.1
KxYKxGKxW signal domain protein; KEGG: sce:YIR019C 1.4e-16 MUC1, FLO11, STA4; GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p); K01178 glucoamylase; Psort location: Extracellular, score: 9.96.
    
 0.538
EHI76309.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.529
EHI75792.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: tgo:TGME49_032360 2.9e-23 RNA polymerase Rpb1 C-terminal repeat domain-containing protein / exonuclease domain-containing protein; Psort location: Extracellular, score: 9.96.
    
 0.499
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.409
Your Current Organism:
Streptococcus sp. F0407
NCBI taxonomy Id: 861455
Other names: S. sp. oral taxon 058 str. F0407, Streptococcus sp. oral taxon 058 str. F0407
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.