| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GAQ94710.1 | GAQ94829.1 | TAGGR_1895 | TAGGR_11015 | NADPH-dependent glutamate synthase beta chain. | Ribose 5-phosphate isomerase B. | 0.547 |
| GAQ94710.1 | fhs | TAGGR_1895 | TAGGR_3159 | NADPH-dependent glutamate synthase beta chain. | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.890 |
| GAQ94710.1 | folD | TAGGR_1895 | TAGGR_2389 | NADPH-dependent glutamate synthase beta chain. | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.626 |
| GAQ94710.1 | gcvH | TAGGR_1895 | TAGGR_1150 | NADPH-dependent glutamate synthase beta chain. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.884 |
| GAQ94710.1 | glyA | TAGGR_1895 | TAGGR_11014 | NADPH-dependent glutamate synthase beta chain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.891 |
| GAQ94710.1 | guaB | TAGGR_1895 | TAGGR_2197 | NADPH-dependent glutamate synthase beta chain. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.617 |
| GAQ94710.1 | purD | TAGGR_1895 | TAGGR_11148 | NADPH-dependent glutamate synthase beta chain. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.484 |
| GAQ94710.1 | purH | TAGGR_1895 | TAGGR_11150 | NADPH-dependent glutamate synthase beta chain. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.862 |
| GAQ94710.1 | purL | TAGGR_1895 | TAGGR_1974 | NADPH-dependent glutamate synthase beta chain. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.887 |
| GAQ94829.1 | GAQ94710.1 | TAGGR_11015 | TAGGR_1895 | Ribose 5-phosphate isomerase B. | NADPH-dependent glutamate synthase beta chain. | 0.547 |
| GAQ94829.1 | fhs | TAGGR_11015 | TAGGR_3159 | Ribose 5-phosphate isomerase B. | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.633 |
| GAQ94829.1 | folD | TAGGR_11015 | TAGGR_2389 | Ribose 5-phosphate isomerase B. | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.681 |
| GAQ94829.1 | gcvH | TAGGR_11015 | TAGGR_1150 | Ribose 5-phosphate isomerase B. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.586 |
| GAQ94829.1 | glyA | TAGGR_11015 | TAGGR_11014 | Ribose 5-phosphate isomerase B. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.988 |
| GAQ94829.1 | guaB | TAGGR_11015 | TAGGR_2197 | Ribose 5-phosphate isomerase B. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.517 |
| GAQ94829.1 | purH | TAGGR_11015 | TAGGR_11150 | Ribose 5-phosphate isomerase B. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.567 |
| GAQ94829.1 | purN | TAGGR_11015 | TAGGR_1246 | Ribose 5-phosphate isomerase B. | Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.567 |
| fhs | GAQ94710.1 | TAGGR_3159 | TAGGR_1895 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | NADPH-dependent glutamate synthase beta chain. | 0.890 |
| fhs | GAQ94829.1 | TAGGR_3159 | TAGGR_11015 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Ribose 5-phosphate isomerase B. | 0.633 |
| fhs | folD | TAGGR_3159 | TAGGR_2389 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.989 |
