Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GAQ94872.1Cytochrome c554 and c-prime. (146 aa)    
Predicted Functional Partners:
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.887
GAQ94873.1
Signal transduction histidine kinase.
     
 0.830
GAQ95038.1
Rhodanese-like domain-containing protein.
    
 0.795
GAQ95039.1
3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains.
    
 0.795
GAQ94875.1
Hypothetical protein.
     
 0.794
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.791
GAQ94874.1
Two-component system, cell cycle response regulator DivK.
       0.780
GAQ94871.1
Hypothetical protein.
    
  0.775
TAGGR_110
Uroporphyrinogen III methyltransferase.
    
  0.756
GAQ95030.1
ABC-type branched-chain amino acid transport system, substrate-binding protein.
 
   
 0.714
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
Server load: low (26%) [HD]