Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GAQ95033.1Nicotinamidase-related amidase. (186 aa)    
Predicted Functional Partners:
GAQ95030.1
ABC-type branched-chain amino acid transport system, substrate-binding protein.
       0.780
GAQ95031.1
PAS domain S-box-containing protein.
       0.780
GAQ95032.1
Response regulator receiver domain-containing protein.
       0.780
GAQ95034.1
Histidinol phosphatase.
       0.780
GAQ95035.1
Putative negative regulator of RcsB-dependent stress response.
       0.780
GAQ95028.1
Heterodisulfide reductase subunit A.
       0.773
GAQ95029.1
TusA-related sulfurtransferase; Belongs to the sulfur carrier protein TusA family.
       0.773
GAQ94766.1
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.720
GAQ95690.1
Anthranilate synthase component 2.
  
 
 0.716
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 
 0.705
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
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