Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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nnrDNAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] (506 aa)    
Predicted Functional Partners:
GAQ93966.1
ADP-ribose pyrophosphatase.
  
 0.966
GAQ95279.1
RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
   
 
 0.894
GAQ95063.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
  
 
 0.828
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.818
pdxJ
Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
       0.659
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
  
 0.657
GAQ94943.1
Starch phosphorylase.
  
   0.645
TAGGR_148
Succinate dehydrogenase; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
  
 0.625
GAQ95276.1
Hypothetical protein; Belongs to the MEMO1 family.
  
   0.616
GAQ95273.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
    0.609
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
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