Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TAGGR_221Methyltransferase, FkbM family. (289 aa)    
Predicted Functional Partners:
TAGGR_227
Capsular polysaccharide transport system ATP-binding protein.
 
     0.825
TAGGR_224
Glycosyltransferase.
     
 0.814
TAGGR_228
Capsular polysaccharide transport system permease protein.
       0.803
TAGGR_225
SLBB domain-containing protein.
       0.786
TAGGR_219
GSCFA family protein.
 
     0.781
TAGGR_220
Hypothetical protein.
       0.773
TAGGR_222
Hypothetical protein.
       0.773
TAGGR_223
Sulfotransferase family protein.
       0.773
TAGGR_226
Capsular polysaccharide transport system permease protein.
       0.773
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.605
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
Server load: low (18%) [HD]