STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)    
Predicted Functional Partners:
GAQ94146.1
acetyl-CoA synthase.
   
 
 0.886
TAGGR_273
Acetyltransferase.
    
 0.876
GAQ93942.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.857
TAGGR_263
Cation/acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.830
TAGGR_264
Uncharacterized membrane protein, DUF485 family.
  
  
 0.826
GAQ94175.1
Pyruvate carboxylase subunit B.
    
 0.819
accD
acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
    
 0.704
TAGGR_269
Cation/acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.701
GAQ95001.1
Pyruvate ferredoxin oxidoreductase gamma subunit.
     
 0.696
GAQ95004.1
Pyruvate ferredoxin oxidoreductase beta subunit.
   
 
 0.693
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
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