acsA protein (Thermodesulfovibrio aggregans)

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acsA

acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)

Predicted Functional Partners:

TAGGR_264

0.883

TAGGR_273

0.873

GAQ94175.1

0.827

GAQ93942.1

0.814

GAQ94146.1

0.798

TAGGR_263

0.796

accD

0.663

GAQ94710.1

0.662

TAGGR_269

0.662

GAQ95678.1

0.652

Your Current Organism:

Thermodesulfovibrio aggregans

NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAQ93942.1	GAQ94146.1	TAGGR_1107	TAGGR_1322	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	acetyl-CoA synthase.	0.836
GAQ93942.1	GAQ94175.1	TAGGR_1107	TAGGR_1354	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Pyruvate carboxylase subunit B.	0.889
GAQ93942.1	GAQ94710.1	TAGGR_1107	TAGGR_1895	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	NADPH-dependent glutamate synthase beta chain.	0.944
GAQ93942.1	GAQ95678.1	TAGGR_1107	TAGGR_3151	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.809
GAQ93942.1	TAGGR_273	TAGGR_1107	TAGGR_273	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	Acetyltransferase.	0.847
GAQ93942.1	accD	TAGGR_1107	TAGGR_378	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.767
GAQ93942.1	acsA	TAGGR_1107	TAGGR_262	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.814
GAQ94146.1	GAQ93942.1	TAGGR_1322	TAGGR_1107	acetyl-CoA synthase.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.836
GAQ94146.1	GAQ94175.1	TAGGR_1322	TAGGR_1354	acetyl-CoA synthase.	Pyruvate carboxylase subunit B.	0.796
GAQ94146.1	GAQ94710.1	TAGGR_1322	TAGGR_1895	acetyl-CoA synthase.	NADPH-dependent glutamate synthase beta chain.	0.898
GAQ94146.1	GAQ95678.1	TAGGR_1322	TAGGR_3151	acetyl-CoA synthase.	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.767
GAQ94146.1	accD	TAGGR_1322	TAGGR_378	acetyl-CoA synthase.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.798
GAQ94146.1	acsA	TAGGR_1322	TAGGR_262	acetyl-CoA synthase.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.798
GAQ94175.1	GAQ93942.1	TAGGR_1354	TAGGR_1107	Pyruvate carboxylase subunit B.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.889
GAQ94175.1	GAQ94146.1	TAGGR_1354	TAGGR_1322	Pyruvate carboxylase subunit B.	acetyl-CoA synthase.	0.796
GAQ94175.1	GAQ94710.1	TAGGR_1354	TAGGR_1895	Pyruvate carboxylase subunit B.	NADPH-dependent glutamate synthase beta chain.	0.893
GAQ94175.1	GAQ95678.1	TAGGR_1354	TAGGR_3151	Pyruvate carboxylase subunit B.	acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.994
GAQ94175.1	TAGGR_273	TAGGR_1354	TAGGR_273	Pyruvate carboxylase subunit B.	Acetyltransferase.	0.789
GAQ94175.1	accD	TAGGR_1354	TAGGR_378	Pyruvate carboxylase subunit B.	acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.988
GAQ94175.1	acsA	TAGGR_1354	TAGGR_262	Pyruvate carboxylase subunit B.	acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.827

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