Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TAGGR_271DNA polymerase-3 subunit epsilon. (233 aa)    
Predicted Functional Partners:
TAGGR_267
CBS domain-containing protein.
 
 
  0.941
GAQ94431.1
DNA polymerase-3 subunit alpha.
    
 0.934
GAQ94307.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
   
 0.929
TAGGR_266
CBS domain-containing protein.
 
 
  0.892
GAQ93977.1
DNA polymerase-3 subunit delta.
  
 
 0.888
dnaX
DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.887
GAQ95790.1
DNA polymerase-3 subunit delta'.
    
 0.887
TAGGR_265
DNA polymerase-3 subunit epsilon.
 
  
 
0.871
TAGGR_269
Cation/acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.853
TAGGR_270
Putative solute:sodium symporter small subunit.
 
     0.825
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
Server load: low (14%) [HD]