Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TAGGR_288Hypothetical protein. (223 aa)    
Predicted Functional Partners:
TAGGR_289
Type I restriction enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
   
 0.953
TAGGR_291
Type I restriction enzyme, S subunit.
 
     0.932
TAGGR_292
Type I restriction enzyme M protein.
 
     0.932
TAGGR_290
Hypothetical protein.
 
     0.779
GAQ94211.1
Tetrapyrrole methylase family protein.
    
  0.590
pyrR
Pyrimidine operon attenuation protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
  0.567
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
  0.567
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
     
  0.567
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.567
GAQ95692.1
Anaerobic ribonucleoside-triphosphate reductase.
     
  0.567
Your Current Organism:
Thermodesulfovibrio aggregans
NCBI taxonomy Id: 86166
Other names: DSM 17283, JCM 13213, T. aggregans, Thermodesulfovibrio aggregans Sekiguchi et al. 2008, Thermodesulfovibrio sp. TGE-P1, strain TGE-P1
Server load: low (10%) [HD]