Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFM25594.1Hypothetical protein; COG: COG1253; Pfam: PF01595,PF00571,PF03471; InterPro: IPR002550. (448 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
    
 0.898
EFM26268.1
5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872,PF00395; InterPro: IPR006179; Belongs to the 5'-nucleotidase family.
    
 0.476
rph
tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
  0.461
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG: COG0138; Pfam: PF02142,PF01808; InterPro: IPR002695.
    
 0.457
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.447
hpt
Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.429
hpt-2
Hypoxanthine phosphoribosyltransferase; COG: COG0634; Pfam: PF00156; InterPro: IPR005904; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.429
ald
Alanine dehydrogenase; COG: COG0686; Pfam: PF05222,PF01262; InterPro: IPR008141; Belongs to the AlaDH/PNT family.
       0.424
EFM25591.1
Hypothetical protein.
       0.422
EFM25593.1
Hypothetical protein.
       0.422
Your Current Organism:
Peptoniphilus duerdenii
NCBI taxonomy Id: 862517
Other names: P. duerdenii ATCC BAA-1640, Peptoniphilus duerdenii ATCC BAA-1640, Peptoniphilus duerdenii WAL 18896
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