STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (457 aa)    
Predicted Functional Partners:
E6O75_ATG03583
Cytoplasmic dynein-like protein 1 heavy chain 1.
    
 0.997
E6O75_ATG10023
Nuclear distribution protein nude.
    
 
 0.949
E6O75_ATG11425
Nuclear movement protein nudC-like.
    
 0.932
E6O75_ATG11470
WD40 repeat-like protein.
   
 0.927
E6O75_ATG01410
Uncharacterized protein.
    
 0.919
E6O75_ATG09689
Putative dynactin subunit 2 protein.
    
 0.908
E6O75_ATG02380
Dynein-associated polypeptide ro-3.
    
 0.904
E6O75_ATG01137
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.883
E6O75_ATG02954
Dynein light intermediate chain.
   
 0.838
E6O75_ATG00663
Glutamine-hydrolyzing asparagine synthase.
    
  0.826
Your Current Organism:
Venturia nashicola
NCBI taxonomy Id: 86259
Other names: V. nashicola
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