STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN12285.1TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: sma:SAV_3036 hypothetical protein; SMART: metal-dependent phosphohydrolase HD region. (462 aa)    
Predicted Functional Partners:
AEN12286.1
Response regulator receiver protein; KEGG: sma:SAV_3035 lipoprotein.
    
0.927
AEN12537.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: sgr:SGR_2001 putative integral membrane phosphodiesterase; SMART: GGDEF domain containing protein; PAS domain containing protein; EAL domain protein.
 
 
 0.872
AEN12030.1
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: sgr:SGR_2612 putative secreted protein; SMART: GGDEF domain containing protein.
 
 
 0.778
AEN12287.1
KEGG: sgr:SGR_2304 hypothetical protein.
       0.777
AEN12283.1
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: sgr:SGR_2306 RNA polymerase sigma factor RpoE; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
   
   0.761
AEN12744.1
GAF sensor hybrid histidine kinase; KEGG: sgr:SGR_1773 putative two-component system sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; response regulator receiver.
  
 
 0.760
AEN12284.1
TIGRFAM: anti-sigma factor; KEGG: sgr:SGR_2305 putative anti-sigma factor.
       0.744
def-3
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.712
AEN11551.1
Diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: PAS fold-3 domain protein; GAF domain protein; GGDEF domain containing protein; KEGG: sgr:SGR_4052 hypothetical protein; SMART: GGDEF domain containing protein; PAS domain containing protein; GAF domain protein.
 
 
 0.682
AEN13985.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: sgr:SGR_709 hypothetical protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein.
  
 0.679
Your Current Organism:
Streptomyces sp. SirexAAE
NCBI taxonomy Id: 862751
Other names: S. sp. SirexAA-E, Streptomyces sp. ACTE, Streptomyces sp. SA3_actE, Streptomyces sp. SirexAA-E
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