STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvCKetol-acid reductoisomerase. (324 aa)    
Predicted Functional Partners:
BMS_1991
Putative hydroxymethylglutaryl-CoA lyase.
  
  
 0.906
tdcB
Threonine dehydratase catabolic.
 
  
 0.859
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.843
pheA
Putative P-protein [includes: chorismate mutase and prephenate dehydrogenase].
 
  
 0.841
BMS_0607
Hypothetical protein.
     
 0.811
BMS_0606
Conserved hypothetical protein.
       0.773
BMS_0610
Putative aminotransferase.
  
  
 0.745
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.719
ilvE
Putative branched-chain amino acid transaminase.
 
  
 0.680
hisF
Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
  
 0.666
Your Current Organism:
Halobacteriovorax marinus
NCBI taxonomy Id: 862908
Other names: Bacteriovorax marinus SJ, Bdellovibrio sp. SJ, H. marinus SJ, Halobacteriovorax marinus SJ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.