STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhCDihydrolipoamide acetyltransferase. (542 aa)    
Predicted Functional Partners:
BMS_0671
Putative dihydrolipoyl dehydrogenase.
 0.999
BMS_1223
Putative 2-oxoisovalerate dehydrogenase, alpha and beta subunits.
 0.999
sucA
2-oxoglutarate dehydrogenase E1 component.
 0.999
pdhAB
Putative pyruvate (oxoisovalerate) Dehydrogenase, alpha-beta fusion; Similar to C-terminus of Bacillus stearothermophilus (Geobacillus stearothermophilus) PdhB pyruvate dehydrogenase E1 component subunit beta (ec 1.2.4.1). UniProt:P21874 (EMBL:X53560) (324 aa) fasta scores: E()=8.4e-39, 39.296% id in 341 aa.
 0.999
lpdA
Putative dihydrolipoamide dehydrogenase.
 0.997
sucC
succinyl-CoA synthetase beta chain (SCS-beta); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.982
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.974
BMS_0437
Putative mercury oxidoreductase.
 0.949
odhB
Putative dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
  
 
0.914
lplA
Putative lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
 
 0.881
Your Current Organism:
Halobacteriovorax marinus
NCBI taxonomy Id: 862908
Other names: Bacteriovorax marinus SJ, Bdellovibrio sp. SJ, H. marinus SJ, Halobacteriovorax marinus SJ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.