STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purCPutative phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (364 aa)    
Predicted Functional Partners:
purE
Putative phosphoribosylaminoimidazole carboxylase catalytic subunit.
  
 
 0.997
purB
Adenylosuccinate lyase.
  
 0.992
purF
Putative amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 
 0.983
purD
Putative phosphoribosylamine--glycine ligase.
  
 
 0.983
purL
Putative phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought t [...]
 
 
 0.948
purH
Putative bifunctional purine biosynthesis protein PurH; Belongs to the PurH family.
 
 
 0.943
purQ
Putative phosphoribosylformylglycinamidine synthase 1.
 
  
 0.939
purM
Putative Phosphoribosylformylglycinamidine cyclo-ligase.
  
  
 0.914
BMS_1939
Putative carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
 
  
 0.868
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.846
Your Current Organism:
Halobacteriovorax marinus
NCBI taxonomy Id: 862908
Other names: Bacteriovorax marinus SJ, Bdellovibrio sp. SJ, H. marinus SJ, Halobacteriovorax marinus SJ
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