Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lpdAPutative dihydrolipoamide dehydrogenase. (466 aa)    
Predicted Functional Partners:
odhB
Putative dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
pdhAB
Putative pyruvate (oxoisovalerate) Dehydrogenase, alpha-beta fusion; Similar to C-terminus of Bacillus stearothermophilus (Geobacillus stearothermophilus) PdhB pyruvate dehydrogenase E1 component subunit beta (ec 1.2.4.1). UniProt:P21874 (EMBL:X53560) (324 aa) fasta scores: E()=8.4e-39, 39.296% id in 341 aa.
 
 0.999
BMS_1223
Putative 2-oxoisovalerate dehydrogenase, alpha and beta subunits.
 
 0.998
pdhC
Dihydrolipoamide acetyltransferase.
 0.996
sucA
2-oxoglutarate dehydrogenase E1 component.
 
 0.995
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.961
gcvP
Glycine dehydrogenase (decarboxylating).
  
 0.959
gcvT
Putative aminomethyltransferase.
 
 0.955
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.919
folD
folD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.915
Your Current Organism:
Halobacteriovorax marinus
NCBI taxonomy Id: 862908
Other names: Bacteriovorax marinus SJ, Bdellovibrio sp. SJ, H. marinus SJ, Halobacteriovorax marinus SJ
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