Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCI_0144Penicillin-binding protein. (739 aa)    
Predicted Functional Partners:
pbp2b
Putative penicillin binding protein 2B.
 
 0.989
pbp2X
Penicillin-binding protein 2/putative cell division protein FtsI.
 
 
0.986
dacA
Penicillin-binding protein 3; Belongs to the peptidase S11 family.
  
 
 0.951
pbp1a
Penicillin binding protein 1A.
  
  
0.927
SCI_1741
Putative penicillin binding protein IIB.
  
  
0.926
gpsB
Hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.912
rodA
Putative rod-shape determing protein RodA; Belongs to the SEDS family.
 
 
 
 0.902
SCI_0283
Surface antigen.
    
 0.901
SCI_1379
Serine-type D-Ala-D-Ala carboxypeptidase.
    
 0.901
SCI_1351
Hypothetical protein; Belongs to the SEDS family.
 
 
 
 0.894
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.