STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaDDiphosphomevalonate decarboxylase. (314 aa)    
Predicted Functional Partners:
SCI_0244
Phosphomevalonate kinase.
 
 
 0.998
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.995
mvk
Mevalonate kinase.
 
  
 0.986
SCI_1459
Putative farnesyl diphosphate synthase/geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 0.954
mvaS
hydroxymethylglutaryl-CoA synthase.
 
 
 0.925
SCI_0246
Putative hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.862
SCI_1115
NTP pyrophosphohydrolase.
  
  
 0.624
lysS
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
      0.543
SCI_0241
Beta-lactamase.
       0.525
SCI_0240
Putative proteinase.
       0.524
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.