STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCPutative DNA repair protein; Belongs to the UPF0758 family. (226 aa)    
Predicted Functional Partners:
mreC
Putative cell shape-determining protein; Involved in formation and maintenance of cell shape.
 
  
 0.657
comFC
Putative competence protein FC.
 
    0.607
hexB
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.557
phoU
Phosphate transport system, regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
       0.544
hexA
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.531
cinA
Putative competence/damage-inducible protein; Belongs to the CinA family.
     
 0.527
comEC
Competence protein.
  
  
 0.515
dprA
DNA protecting protein.
  
  
 0.484
recN
Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.469
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
   
 0.408
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
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