STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (327 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.978
mleS
Malate dehydrogenase.
  
 0.947
acoB
Putative acetoin dehydrogenase.
  
 0.939
ppdK
Pyruvate phosphate, orthophosphate dikinase.
  
 
 0.933
pox1
Pyruvate oxidase.
  
 0.931
acoA
Pyruvate dehydrogenase E1 component subunit alpha.
  
 
 0.930
pfl
Formate C-acetyltransferase.
  
 
 0.922
SCI_1361
Pyruvate formate lyase.
  
 
 0.922
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.913
tkt
Putative transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.879
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.