STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiAHypothetical protein; Involved in cell division and chromosome segregation. (303 aa)    
Predicted Functional Partners:
SCI_1025
Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
  
 0.930
rapZ
Hypothetical protein; Displays ATPase and GTPase activities.
 
  
 0.902
ylxM
Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
  
 0.736
SCI_1837
Hypothetical protein; Belongs to the UPF0297 family.
  
     0.666
SCI_1192
Hypothetical protein.
  
     0.643
polC
DNA polymerase III subunit alpha, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
     0.640
pkn
Putative serine/threonine protein kinase.
 
   
 0.600
asp_1
Hypothetical protein.
  
     0.545
ndk
Nucleoside diphosphate kinase.
       0.477
codY
GTP-sensing transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
     0.440
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.