Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
nreCPutative two-component response transcriptional regulator. (227 aa)    
Predicted Functional Partners:
desK_2
Putative two-component sensor histidine kinase.
 
 0.979
SCI_1699
Putative periplasmic sugar-binding protein.
 
  
 0.936
SCI_1696
Putative sugar-binding periplasmic protein.
 
  
 0.931
SCI_0437
Putative histidine kinase.
 
 
 0.911
SCI_1695
PTS system, sugar-specific IIA component.
 
     0.773
manY
Phosphotransferase system, IIC component.
 
     0.760
SCI_1691
Hypothetical protein.
 
     0.751
levE_2
PTS system, sugar-specific IIB component.
 
     0.750
manZ_3
Phosphotransferase system, sugar-specific component IID.
 
     0.646
saeR
DNA-binding response regulator.
 
 
 0.514
Your Current Organism:
Streptococcus constellatus
NCBI taxonomy Id: 862969
Other names: S. constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis C1050, Streptococcus constellatus subsp. pharyngis str. C1050, Streptococcus constellatus subsp. pharyngis strain C1050
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