Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lplALipoyltransferase and lipoate-protein ligase. (329 aa)    
Predicted Functional Partners:
acoL
Dihydrolipoamide dehydrogenase.
 
 0.996
acoC
Pyruvate dehydrogenase E2 component.
 
 0.985
acoB
Putative acetoin dehydrogenase.
 
  
 0.895
acoA
Pyruvate dehydrogenase E1 component subunit alpha.
 
  
 0.820
merA
Pyridine nucleotide-disulfide oxidoreductase.
 
  
 0.611
birA
Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
  
 0.515
gor
Glutathione reductase.
 
  
 0.493
SANR_1058
Amino acid transferase.
  
   0.445
mraW
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
   0.417
ucpA
Oxidoreductase.
  
  
 0.409
Your Current Organism:
Streptococcus anginosus
NCBI taxonomy Id: 862971
Other names: S. anginosus C238, Streptococcus anginosus C238, Streptococcus anginosus str. C238, Streptococcus anginosus strain C238
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