Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acoBPutative acetoin dehydrogenase. (330 aa)    
Predicted Functional Partners:
acoL
Dihydrolipoamide dehydrogenase.
 
 0.999
acoC
Pyruvate dehydrogenase E2 component.
 0.999
acoA
Pyruvate dehydrogenase E1 component subunit alpha.
 0.999
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.965
hdhL
Putative Malate/lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.965
pfl
Formate C-acetyltransferase.
   
 
 0.939
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.925
pox1
Pyruvate oxidase; Belongs to the TPP enzyme family.
  
 
 0.920
ppdK
Pyruvate phosphate, orthophosphate dikinase.
    
 0.918
lplA
Lipoyltransferase and lipoate-protein ligase.
 
  
 0.895
Your Current Organism:
Streptococcus anginosus
NCBI taxonomy Id: 862971
Other names: S. anginosus C238, Streptococcus anginosus C238, Streptococcus anginosus str. C238, Streptococcus anginosus strain C238
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