STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manAMannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family. (314 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.970
scrK
Putative fructokinase.
 
 
 0.965
nagB
Putative glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.947
manL
Putative phosphotransferase system, mannose-specific EIIAB.
 
  
 0.945
glmS
D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.934
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.933
manM
PTS system, mannose-specific IIC component.
 
  
  0.930
manN
PTS system, mannose-specific IID component.
 
  
  0.924
SANR_0072
Putative PTS system, mannose-specific IIA component.
    
 0.909
fruA
Putative PTS system, fructose-specific enzyme IIABC component.
  
  
 0.909
Your Current Organism:
Streptococcus anginosus
NCBI taxonomy Id: 862971
Other names: S. anginosus C238, Streptococcus anginosus C238, Streptococcus anginosus str. C238, Streptococcus anginosus strain C238
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