node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHR70244.1 | EHR70245.1 | BurJ1DRAFT_1372 | BurJ1DRAFT_1373 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative enzyme of heme biosynthesis; PFAM: HemX. | 0.971 |
EHR70244.1 | EHR70246.1 | BurJ1DRAFT_1372 | BurJ1DRAFT_1374 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative enzyme of heme biosynthesis; PFAM: HemY protein N-terminus. | 0.833 |
EHR70244.1 | EHR71045.1 | BurJ1DRAFT_1372 | BurJ1DRAFT_2206 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.796 |
EHR70244.1 | EHR72131.1 | BurJ1DRAFT_1372 | BurJ1DRAFT_3322 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.890 |
EHR70244.1 | EHR72482.1 | BurJ1DRAFT_1372 | BurJ1DRAFT_3677 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.799 |
EHR70244.1 | EHR73282.1 | BurJ1DRAFT_1372 | BurJ1DRAFT_4494 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.946 |
EHR70244.1 | hemA | BurJ1DRAFT_1372 | BurJ1DRAFT_4369 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.796 |
EHR70244.1 | hemC | BurJ1DRAFT_1372 | BurJ1DRAFT_1371 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.999 |
EHR70244.1 | hemE | BurJ1DRAFT_1372 | BurJ1DRAFT_0191 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.825 |
EHR70244.1 | hemL | BurJ1DRAFT_1372 | BurJ1DRAFT_4242 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.814 |
EHR70245.1 | EHR70244.1 | BurJ1DRAFT_1373 | BurJ1DRAFT_1372 | Putative enzyme of heme biosynthesis; PFAM: HemX. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.971 |
EHR70245.1 | EHR70246.1 | BurJ1DRAFT_1373 | BurJ1DRAFT_1374 | Putative enzyme of heme biosynthesis; PFAM: HemX. | Putative enzyme of heme biosynthesis; PFAM: HemY protein N-terminus. | 0.979 |
EHR70245.1 | EHR71045.1 | BurJ1DRAFT_1373 | BurJ1DRAFT_2206 | Putative enzyme of heme biosynthesis; PFAM: HemX. | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.743 |
EHR70245.1 | EHR72131.1 | BurJ1DRAFT_1373 | BurJ1DRAFT_3322 | Putative enzyme of heme biosynthesis; PFAM: HemX. | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.848 |
EHR70245.1 | EHR72482.1 | BurJ1DRAFT_1373 | BurJ1DRAFT_3677 | Putative enzyme of heme biosynthesis; PFAM: HemX. | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.743 |
EHR70245.1 | EHR73282.1 | BurJ1DRAFT_1373 | BurJ1DRAFT_4494 | Putative enzyme of heme biosynthesis; PFAM: HemX. | PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.921 |
EHR70245.1 | hemA | BurJ1DRAFT_1373 | BurJ1DRAFT_4369 | Putative enzyme of heme biosynthesis; PFAM: HemX. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.532 |
EHR70245.1 | hemC | BurJ1DRAFT_1373 | BurJ1DRAFT_1371 | Putative enzyme of heme biosynthesis; PFAM: HemX. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.996 |
EHR70245.1 | hemE | BurJ1DRAFT_1373 | BurJ1DRAFT_0191 | Putative enzyme of heme biosynthesis; PFAM: HemX. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.825 |
EHR70245.1 | hemL | BurJ1DRAFT_1373 | BurJ1DRAFT_4242 | Putative enzyme of heme biosynthesis; PFAM: HemX. | Glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.720 |