STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHR72373.1Uncharacterized protein involved in chromosome partitioning; PFAM: Domain of unknown function (DUF802). (670 aa)    
Predicted Functional Partners:
EHR72374.1
PFAM: Protein of unknown function (DUF3348).
 
     0.953
EHR72371.1
PFAM: Protein of unknown function (DUF2894).
 
     0.952
EHR72372.1
Flagellar motor protein; PFAM: OmpA family.
 
     0.951
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.872
parC
DNA topoisomerase IV, A subunit, proteobacterial; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
 
 0.872
EHR71974.1
Acyl carrier protein; PFAM: Phosphopantetheine attachment site.
   
   0.854
EHR71979.1
Phosphopantetheine-containing protein; PFAM: Phosphopantetheine attachment site.
   
   0.854
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
   0.854
EHR73099.1
PFAM: Histone H1-like nucleoprotein HC2.
  
     0.618
EHR72378.1
DnaJ-like protein; PFAM: DnaJ domain.
   
   0.565
Your Current Organism:
Burkholderiales bacterium JOSHI001
NCBI taxonomy Id: 864051
Other names: B. bacterium JOSHI_001, Burkholderiales bacterium JOSHI_001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.