STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBHelicase-exonuclease AddAB, AddB subunit; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1154 aa)    
Predicted Functional Partners:
addA
Recombination helicase AddA; ATP-dependent DNA helicase.
 
 
 0.999
AGK97129.1
DNA/RNA helicase, superfamily I; PFAM: UvrD/REP helicase.
  
 
 0.923
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.645
AGK97241.1
Putative HD superfamily hydrolase; PFAM: HD domain; OB-fold nucleic acid binding domain.
 
     0.553
AGK97206.1
Putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A).
       0.533
AGK98458.1
ATPase involved in DNA repair.
 
  
 0.498
AGK97095.1
Putative SAM-dependent methyltransferase; PFAM: Family of unknown function (DUF633).
 
     0.497
recX
Hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
 
   
 0.454
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.447
AGK97820.1
PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
     
 0.439
Your Current Organism:
Clostridium pasteurianum
NCBI taxonomy Id: 86416
Other names: C. pasteurianum BC1, Clostridia isolate BC1, Clostridium pasteurianum BC1, Clostridium pasteurianum str. BC1, Clostridium pasteurianum strain BC1, Clostridium sp. ATCC 53464, Clostridium sp. BC1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.