node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGK95446.1 | AGK99253.1 | Clopa_0386 | Clopa_4546 | Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase. | Hypothetical protein; PFAM: UvrB/uvrC motif. | 0.672 |
AGK95446.1 | mcsB | Clopa_0386 | Clopa_4545 | Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase. | Arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. | 0.674 |
AGK96531.1 | AGK99253.1 | Clopa_1605 | Clopa_4546 | ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; Belongs to the ClpA/ClpB family. | Hypothetical protein; PFAM: UvrB/uvrC motif. | 0.636 |
AGK96531.1 | AGK99254.1 | Clopa_1605 | Clopa_4547 | ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; Belongs to the ClpA/ClpB family. | PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family. | 0.715 |
AGK96531.1 | clpP | Clopa_1605 | Clopa_1636 | ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.839 |
AGK96531.1 | mcsB | Clopa_1605 | Clopa_4545 | ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; Belongs to the ClpA/ClpB family. | Arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. | 0.771 |
AGK99251.1 | AGK99253.1 | Clopa_4544 | Clopa_4546 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | Hypothetical protein; PFAM: UvrB/uvrC motif. | 0.974 |
AGK99251.1 | AGK99254.1 | Clopa_4544 | Clopa_4547 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family. | 0.935 |
AGK99251.1 | AGK99255.1 | Clopa_4544 | Clopa_4548 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.538 |
AGK99251.1 | clpP | Clopa_4544 | Clopa_1636 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.913 |
AGK99251.1 | disA | Clopa_4544 | Clopa_4542 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | Putative nucleic-acid-binding protein (contains the HHH domain); Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | 0.670 |
AGK99251.1 | mcsB | Clopa_4544 | Clopa_4545 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | Arginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. | 0.971 |
AGK99251.1 | radA | Clopa_4544 | Clopa_4543 | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.747 |
AGK99253.1 | AGK95446.1 | Clopa_4546 | Clopa_0386 | Hypothetical protein; PFAM: UvrB/uvrC motif. | Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase. | 0.672 |
AGK99253.1 | AGK96531.1 | Clopa_4546 | Clopa_1605 | Hypothetical protein; PFAM: UvrB/uvrC motif. | ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; Belongs to the ClpA/ClpB family. | 0.636 |
AGK99253.1 | AGK99251.1 | Clopa_4546 | Clopa_4544 | Hypothetical protein; PFAM: UvrB/uvrC motif. | ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; Belongs to the ClpA/ClpB family. | 0.974 |
AGK99253.1 | AGK99254.1 | Clopa_4546 | Clopa_4547 | Hypothetical protein; PFAM: UvrB/uvrC motif. | PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family. | 0.958 |
AGK99253.1 | AGK99255.1 | Clopa_4546 | Clopa_4548 | Hypothetical protein; PFAM: UvrB/uvrC motif. | Hypothetical protein. | 0.542 |
AGK99253.1 | clpB | Clopa_4546 | Clopa_3446 | Hypothetical protein; PFAM: UvrB/uvrC motif. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.716 |
AGK99253.1 | disA | Clopa_4546 | Clopa_4542 | Hypothetical protein; PFAM: UvrB/uvrC motif. | Putative nucleic-acid-binding protein (contains the HHH domain); Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | 0.709 |