STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sojCobQ/CobB/MinD/ParA nucleotide binding domain protein; COG: COG1192; Pfam: PF01656; InterPro: IPR002586. (255 aa)    
Predicted Functional Partners:
spoOJ
ParB-like protein; COG: COG1475; Pfam: PF02195; InterPro: IPR004437; Belongs to the ParB family.
 
 
 0.978
EFM39054.1
ParB-like protein; Pfam: PF02195.
 
 
 0.969
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.634
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
    0.618
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.529
ligA
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.484
EFM39050.1
Hypothetical protein.
 
  
 0.479
guaB
Inosine 5-monophosphate dehydrogenase; COG: COG0516; Pfam: PF00478,PF00571; InterPro: IPR013785.
   
 
 0.472
EFM38795.1
Phage integrase SAM-like domain protein; Pfam: PF02899,PF00589; InterPro: IPR013762; Belongs to the 'phage' integrase family.
 
   
 0.465
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.464
Your Current Organism:
Eubacterium yurii
NCBI taxonomy Id: 864565
Other names: Eubacterium yurii subsp. margaretiae ATCC 43715, Eubacterium yurii subsp. margaretiae str. ATCC 43715, Eubacterium yurii subsp. margaretiae strain ATCC 43715, [. yurii subsp. margaretiae ATCC 43715, [Eubacterium] yurii subsp. margaretiae ATCC 43715
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