STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ01508.1PFAM: Adenylate and Guanylate cyclase catalytic domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR019734:IPR001054; KEGG: gfo:GFO_0018 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide repeat; SPTR: Secreted protein containing adenylate/guanylate cyclase catalytic domain; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)    
Predicted Functional Partners:
EHQ02699.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 007891:IPR013655:IPR013656; KEGG: fba:FIC_01552 two-component system sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; CHASE3; PAS fold-3; PAS fold-4; SMART: ATP-binding region, ATPa [...]
  
 0.912
EHQ02924.1
PFAM: CheB methylesterase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CheR methyltransferase, SAM binding domain; His Kinase A (phosphoacceptor) domain; CheR methyltransferase, all-alpha domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000014:IPR000780:IPR001610:IPR003661:IPR 003594:IPR000673:IPR013767:IPR013656:IPR013655; KEGG: gfo:GFO_1684 two-component system sensor histidine kinase/methyl-esterase/transferase hybrid; PFAM: ATP-binding region, ATPase-like; PAS fold-3; Signal transduction response re [...]
   
 0.904
EHQ02965.1
PFAM: HD domain; InterPro IPR006674; KEGG: gfo:GFO_2662 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Putative uncharacterized protein.
     0.891
EHQ03508.1
Histidine kinase; PFAM: Y_Y_Y domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003594:IPR001789:IPR 018060; KEGG: gfo:GFO_2999 two-component system sensor histidine kinase/response regulator hybrid; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction [...]
 
 0.859
EHQ01520.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Protein kinase domain; GAF domain; COGs: COG3899 ATPase; InterPro IPR002290:IPR001054:IPR017442:IPR003018; KEGG: ter:Tery_2857 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Serine/threonine-protein kinase-like domain; GAF; SMART: Serine/threonine-protein kinase domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Serine/threonine kinase with two-component sensor domain.
 
 
0.847
EHQ03416.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: gfo:GFO_2705 two-component system sensor histidine kinase/response regulator hybrid; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1 [...]
   
 0.827
EHQ03131.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734:IPR006597:IPR001440:IPR013105; KEGG: bpo:BP951000_1446 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; Sel1-like; SPTR: TPR domain-containing protein.
 
 
 0.792
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.785
EHQ01507.1
KEGG: mtt:Ftrac_1354 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
EHQ02962.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: lby:Lbys_1798 adenylate/guanylate cyclase; PFAM: Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Signal transduction response regulator, receiver region; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Serine/threonine protein kinase/response regulator/adenylate cyclase.
  
 
 
0.762
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.