STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHQ02147.1Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; InterPro IPR004843; KEGG: zpr:ZPR_0251 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: Putative secreted protein; manually curated. (365 aa)    
Predicted Functional Partners:
EHQ01520.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Protein kinase domain; GAF domain; COGs: COG3899 ATPase; InterPro IPR002290:IPR001054:IPR017442:IPR003018; KEGG: ter:Tery_2857 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Serine/threonine-protein kinase-like domain; GAF; SMART: Serine/threonine-protein kinase domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Serine/threonine kinase with two-component sensor domain.
    
 0.921
EHQ02699.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 007891:IPR013655:IPR013656; KEGG: fba:FIC_01552 two-component system sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; CHASE3; PAS fold-3; PAS fold-4; SMART: ATP-binding region, ATPa [...]
  
 
 0.868
EHQ03131.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734:IPR006597:IPR001440:IPR013105; KEGG: bpo:BP951000_1446 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; Sel1-like; SPTR: TPR domain-containing protein.
   
 0.863
EHQ02935.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG5616 integral membrane protein; InterPro IPR018060:IPR019734:IPR000005:IPR001440; KEGG: fbc:FB2170_05330 putative serine/threonine kinase; PFAM: Helix-turn-helix, AraC type; Tetratricopeptide TPR-1; SMART: Helix-turn-helix, AraC domain; Tetratricopeptide repeat; SPTR: Probable serine/threonine kinase.
  
 
  0.771
EHQ03416.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: gfo:GFO_2705 two-component system sensor histidine kinase/response regulator hybrid; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1 [...]
  
 
 0.771
EHQ01704.1
KEGG: zpr:ZPR_0252 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.770
EHQ01705.1
Secretin/TonB short domain-containing protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TIGRFAM: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; TonB-linked outer membrane protein, SusC/RagA family; InterPro IPR011662; KEGG: zpr:ZPR_0253 TonB-dependent receptor Plug domain protein; PFAM: Secretin/TonB, short N-terminal; SPTR: TonB-dependent Receptor Plug domain protein; manually curated.
 
     0.763
EHQ03508.1
Histidine kinase; PFAM: Y_Y_Y domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003594:IPR001789:IPR 018060; KEGG: gfo:GFO_2999 two-component system sensor histidine kinase/response regulator hybrid; PFAM: ATP-binding region, ATPase-like; Two component regulator three Y; Two component regulator propeller; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction [...]
  
 
 0.754
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.749
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.740
Your Current Organism:
Gillisia limnaea
NCBI taxonomy Id: 865937
Other names: G. limnaea DSM 15749, Gillisia limnaea DSM 15749, Gillisia limnaea R-8282, Gillisia limnaea str. DSM 15749, Gillisia limnaea strain DSM 15749
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